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VMD v Humphrey et al was used
2020-07-23
VMD v1.9.2 (Humphrey et al., 1996) was used to analyze the MD trajectories, salt bridge interactions and secondary structure information from each frame. Once the model was optimized, the topological diagram and area and volume of protein cavities were analyzed using PDBsum (Laskowski, 2009) and CAS
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In this contribution herein we report our newly devised
2020-07-23
In this contribution, herein we report our newly devised molecular probes with a triazole linked benzimidazole-indole-thiazolium mixed heterocyclic framework as depicted in Scheme 1. Their architecture was designed to achieve the advancement in selectivity and specificity toward DNA matrix over RNA
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Ingested folate needs to be chemically modified in order to
2020-07-23
Ingested folate needs to be chemically modified in order to become a one carbon donor for cell metabolism. Firstly, folate turns to dihydrofolic Adenosine-5\'-diphosphate (DHF), it is then converted into tetrahydrofolate (THF) by the dihydrofolate reductase enzyme (DHFR) and finally converted into
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br General Characteristics of the
2020-07-23
General Characteristics of the Type II Dehydrogenases Alternative NAD(P)H dehydrogenases conduct the reaction of the rotenone-insensitive oxidation of cytosolic and mitochondrial matrix NADH and/or NADPH (Fig. 1) (Melo et al., 2004, Rasmusson et al., 2004, Rasmusson et al., 2008). They catalyze t
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The fibrillogenesis process of collagen is
2020-07-23
The fibrillogenesis process of collagen is understood to initiate in the extracellular space near the plasma membrane where secretory vesicles form regions of deep invagination. However, it is not clear how and when collagen-binding proteins interact with collagen molecules during fibrillogenesis or
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For the first time the V carinata transcriptome was
2020-07-23
For the first time, the V. carinata transcriptome was analyzed and its transcript coding sequences comprehensively characterized. The non-redundant contigs encoding putative CysPs were identified and their prostaglandin receptor patterns in different tissues were investigated. Our study show that f
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PU-H71 synthesis While lowering the TID exposure of electron
2020-07-23
While lowering the TID exposure of electronics is fairly straightforward, there are other PU-H71 synthesis induced effects that are not as easily mitigated, especially with COTS components. Single Event Effects (SEE) occur when a high-energy particle strikes the active area of an integrated circuit
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br Conclusions br Introduction Today
2020-07-23
Conclusions Introduction Today – just as for the past 50 years – the most commonly used repellent in the world is DEET (Fradin, 1998; Pickett et al., 2008). The active ingredient, N,N-Diethyl-m-toluamide, is an oily synthetic substance applied topically to the skin in order to alter the host f
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Table gives the list of components which will
2020-07-22
Table 1 gives the list of components which will be modeled. Transient Voltage Suppressor (TVS) as well as passive elements will be also modeled. For each component, we will choose the EMC (emission and immunity) and transient immunity measurement method adapted to extract the component model. A com
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Another clinical study indicated the daily consumption of
2020-07-22
Another clinical study indicated the daily consumption of green tea with low concentrations of theanine and catechin would improve cognitive function (Ide et al., 2014). Further, in a double blind randomized clinical study involving 102 patients, the Hypericum extract was examined in terms of effica
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br Results br Discussion Mucosal barriers are constitutively
2020-07-22
Results Discussion Mucosal barriers are constitutively challenged by various stimuli, and the homeostasis of mucosal barriers both at steady state and upon challenge are maintained by tissue-resident immune dgat1 inhibitor (Kurashima et al., 2013, Okumura and Takeda, 2016). ILC3s are found in
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br Discussion The aim of this study was to
2020-07-22
Discussion The aim of this study was to establish staining protocols to enhance the visualization of a dental filling or its remaining in forensic dentistry. Teeth and dental materials resist to most of environmental and disaster conditions, therefore the forensic odontology exam is essential in
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The all NTP pyrophosphatase and NUDIX families maintain the
2020-07-22
The all-α NTP pyrophosphatase and NUDIX families maintain the deoxynucleotide triphosphate (dNTP) pool balance, limit the incorporation of harmful nucleotides, and represent a promising therapeutic approach to develop anticancer and immunosuppressive agents., , , , Among these housekeeping enzymes
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In the Cu bioassay notwithstanding
2020-07-22
In the Cu bioassay, notwithstanding the absence of significant Cu bioaccumulation in bulk tissues over the 96-h exposure period (less than 2-fold difference in tissue Cu between controls and the second-highest treatment), T-ChE activity increased with Cu concentration in gill and, to a lesser extent
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PTP Inhibitor IV synthesis br Conflicts of interest br Intro
2020-07-21
Conflicts of interest Introduction Diacylglycerols (DAGs) and phosphatidic PTP Inhibitor IV synthesis (PA) play fundamental roles in biology as basic components of membranes, intermediates in lipid metabolism, and secondary messengers in cellular signaling (Carrasco and Merida, 2007, Fang et
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