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Recently it has been shown
2020-12-01
Recently, it has been shown that among the ELR (+) chemokines mentioned above, particularly IL-8 induces neutrophil migration via CXCR-1 chemokine receptor. For example, Godaly et al. [18] reported the potent role of CXCR-1 chemokine receptor in the process of neutrophil migration across epithelial
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In the Cu bioassay notwithstanding the absence of significan
2020-12-01
In the Cu bioassay, notwithstanding the absence of significant Cu bioaccumulation in bulk tissues over the 96-h exposure period (less than 2-fold difference in tissue Cu between controls and the second-highest treatment), T-ChE activity increased with Cu concentration in gill and, to a lesser extent
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Furthermore software engineering practices are important for
2020-12-01
Furthermore, software engineering practices are important for addressing productivity problems in scientific software. Even though the speed of the hardware is rapidly increasing, the additional complexity makes it more difficult for scientists to be productive developers. According to Faulk et al.,
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br Experimental br Results and discussion
2020-12-01
Experimental Results and discussion Fig. 2 shows schematically the fundamentals of the developed HRP-P4-(P4)-anti-P4-Protein-G-MBs/SPCE immunosensor. Oriented immobilization of anti-P4 was accomplished onto Protein G-MBs due to the Protein G binding ability with the Fc region of many mammals i
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Using characteristic features of ECM proteins and
2020-12-01
Using characteristic features of ECM proteins and a computational pipeline combining interrogation of protein and gene databases, we previously defined the matrisome as the ensemble of ECM and ECM-associated proteins [[16], [17], [18]]. In mammals, the matrisome represents 4% of the genome, or appro
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In summary synthetic routes with
2020-12-01
In summary, synthetic routes with moderate to high yields have been developed to produce difluoro-dioxolo-benzoimidazol-benzamides including reference standards and , and -desmethylated precursors and , and carbon-11-labeled difluoro-dioxolo-benzoimidazol-benzamides target tracers [C] and [C]. The r
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br Materials and methods br Results and discussion br
2020-11-30
Materials and methods Results and discussion Conclusions The fabrication and characterization of AMCs reinforced with SiC and RHA was done in this study. Following conclusions are drawn from the above study: Conflict of interest Authors' contributions Introduction Industrialisatio
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The effect of transformation of the linker Y between the
2020-11-30
The effect of transformation of the linker Y between the carboxylic Thienoguanosine residue and the phenyl moiety of 2b was also investigated, and is illustrated in Table 5. Analogs 2b, 16, and 17, possessing conformationally restricted carboxylic acid residues, tended to show stronger antagonist a
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After crown formation root development begins via the intera
2020-11-30
After crown formation, root development begins via the interaction between the Hertwig root sheath (HERS) and the dental papilla, which differentiates into odontoblasts and forms dentin and pulp. HERS is associated with the number of roots and their morphology . The stem cells from the apical papill
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These data from developing brain
2020-11-28
These data from developing N1-Methylpseudo-UTP are in contrast to noradrenergic receptor regulation in the adult brain. In adult animals, a persistent increase in the α2-AR high affinity state is elicited as a result of DSP-4 lesion or reserpinization, as measured by [3H]clonidine binding to membra
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The promoter regions of all
2020-11-28
The promoter regions of all MdDGKs examined here included many hormone-responsive and stress-responsive elements, such as ABRE, MBS, TC-rich repeats, HSE, and LTR. Despite assumptions about how those promoters might control expression in response to environment stimuli, we found several exceptions.
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Gene amplification PCR amplifications were performed using g
2020-11-28
Gene amplification. PCR amplifications were performed using genomic DNA from the different organisms studied as template and two degenerate oligonucleotides (PP1 and PP2) as primersPP1 corresponded to the sense codons of the amino 91 5 motif AGGI(A/S)EM, and PP2 to the antisense sequence of the mot
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bradykinin receptor antagonist In summary the reduction of o
2020-11-28
In summary, the reduction of one or more pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, IL-8 was observed in almost all the monoterpenes studied. Increased levels of the anti-inflammatory cytokine IL-10 was shown to play a prominent function in the anti-inflammatory effect of monoterpenes,
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The levels of circulating pro inflammatory cytokines are mar
2020-11-28
The levels of circulating pro-inflammatory cytokines are markedly elevated in ESRD, and have been speculated to play an important role as causative factors in a number of uremic complications [37]. The impairment of phagocyte functions and deregulated cytokine productions are highly prevalent in CRF
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In this study we observed alterations in mRNA levels
2020-11-28
In this study, we observed alterations in mRNA levels of CRF receptors in the PFCx and Hip during the development of sensitization. In particular, in the Hip both CRF receptors showed significantly increased PF 4800567 hydrochloride when the sensitization condition was established. Similarly, CRF2
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