• The deletion of q seen in

  2019-05-07

  

  The deletion of 14q seen in our patient included the IGH locus at 14q32.33. This is noteworthy, because loss of 14q has been reported as a recurrent aberration acquired during the natural history of CLL. The acquisition of a del(14) may thus be indicative of CLL in transformation. In a study of a la

• br Current approaches to HIV prevention typically target

  2019-05-07

  

  Current approaches to HIV prevention typically target people who are identified as, or self-identify, with being at risk. In Africa, 74% of new HIV infections are among adolescent girls aged 15–19 years, and AIDS-related illnesses are the leading cause of death among adolescent girls and women of

• The patient started FOLFOX chemotherapy at another

  2019-05-07

  

  The patient started FOLFOX chemotherapy at another institute on September 14, 2015. However, he suddenly lost consciousness and his blood pressure plummeted; the electrocardiogram monitor showed ventricular tachycardia. After cardiopulmonary resuscitation, he regained spontaneous circulation and was

• Validation study findings showed that knowledge KR had moder

  2019-05-07

  

  Validation study findings showed that knowledge (KR20=0.58) had moderate internal consistency. Even though this was fairly acceptable, the knowledge domain was considered a good test as KR20 tends to result in more conservative estimates than Cronbach’s alpha [28]. Enhancing the reliability of a que

• Partamos primero de la v ctima sacrificial Fernando Valle De

  2019-05-07

  

  Partamos primero de la víctima sacrificial: Fernando Valle. Desde su juventud, Fernando es aislado de la sociedad. Su familia lo rechaza, como explica al médico-narrador (120). Una víctima “sacrificable”, según Girard, tiene que ser alguien diferenciado de la sociedad; las víctimas son seres margina

• Therefore the patient was diagnosed with BIP

  2019-05-06

  

  Therefore, the patient was diagnosed with BIP, and steroid therapy with oral prednisolone at 40mg/day (0.5mg/kg/day) was initiated. The patient responded well to steroid therapy. After several weeks, his respiratory condition improved to Hugh–Jones class I. Since the imaging findings improved and th

• Findings from the last major systematic review

  2019-05-06

  

  Findings from the last major systematic review of the global prevalence of echocardiographic rheumatic Senexin B disease showed that the highest calculated regional prevalence was in sub-Saharan Africa (5·7 cases per 1000 people), indigenous people in the Pacific islands, Australia, and New Zealand

• br It s that time of year again when we

  2019-05-06

  

  It\'s that time of year again when we ask readers to submit photographs for our annual Highlights photography competition. We are looking for striking images that arrest our attention about any topic in medicine, from global health to clinical medicine, from the individual person to populations. A

• En muchos estudios fuera del campo posfundacional

  2019-05-06

  

  En muchos estudios (fuera del campo posfundacional) la referencia eletriptan Laclau proviene de teorizar el “discurso populista”. Existe un frecuente equívoco que es interpretar esto como una reducción a una especie de lenguaje populista. Al respecto, el esfuerzo de Laclau por establecer el estatus

• Leptin synthesized in adipocytes is a regulator of fat

  2019-05-06

  

  Leptin, synthesized in adipocytes, is a regulator of fat metabolism and reproduction [7]. The levels of leptin correlate with body fat mass and show a wide variation in individuals. In the bone marrow microenvironment, the leptin secreting adipocytes occupy a significant part [8]. Leptin stimulates

• Non communicable disease behavioural risk factors such

  2019-05-06

  

  Non-communicable disease behavioural risk factors such as tobacco smoking, heavy alcohol consumption, physical inactivity, and unhealthy eating are socially patterned in high-income countries, with individuals of low socioeconomic status generally experiencing a higher burden of risk factors. Howev

• br Management of warfarin during pacemaker implantable cardi

  2019-05-06

  

  Management of warfarin during pacemaker/implantable cardioverter defibrillator insertion Until recently, warfarin use was halted before PM/ICD insertion and the patient was bridged with intravenous (IV) unfractionated heparin or subcutaneous low-molecular-weight heparin (LMWH) if the thromboembol

• br Results Compared to the respective untreated groups the

  2019-05-06

  

  Results Compared to the respective untreated groups, the VT duration was shorter in clonidine-treated ETB-deficient rats during phase I and in wild-type rats during phase II (Fig. 1A). Heart rate (HR) increased in both untreated groups, but this response was blunted after clonidine, mainly in ETB

• br Autophagy and lipid metabolism

  2019-05-06

  

  Autophagy and lipid metabolism LD formation is an indispensable step in lipid metabolism. The Atg8/LC3 conjugation system is essential for autophagosome membrane formation. However, some evidence suggests that Atg8/LC3 conjugation is also involved in LD formation. Indeed, LD formation is suppress

• Social determinants are the lived conditions ie

  2019-05-06

  

  Social determinants are the lived conditions (ie, social and economic) that influence wellbeing, and environmental influences on behaviour are those assessed with the health behaviour theory. Stages of change models (ie, those that recognise health behaviour as a series of progressive steps leading

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