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regulator of g protein signaling In contrast median Cu level
2019-07-01
In contrast, median Cu level (0.73 mg/L) in our study was approximately 50% lower than that in maternal blood (1.47 mg/L). Our result is consistent with several previously published studies, which showed a 50–60% decrease in Cu level in the fetus. The observed decrease in fetal Cu, a major metallic
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Early repolarization is often also observed in
2019-07-01
Early repolarization is often also observed in Brugada syndrome patients [30–34]. In this study, 34% of Brugada syndrome patients exhibited early repolarization in inferolateral leads. Clinical characteristics, inducibility, and arrhythmic event rate were similar between patients with and without ea
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In the case reported by Goldstein
2019-07-01
In the case reported by Goldstein et al. [2], a Riata ST lead (St. Jude Medical, Sylmar, CA, USA) was used. The authors did not mention whether the lead was a dual-coil system or not. If the lead was a single-coil system, the possibility of an HV short circuit between the RV coil conductor and the d
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Brefeldin A The efficiency of additional strategies
2019-07-01
The efficiency of 2 additional strategies for eliminating the substrate for AF maintenance in addition to PVI has been described. Linear lesions are commonly made at the roof between the contralateral superior PVs (roof line), and at the isthmus between the mitral valve and the left inferior PV (mit
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Introduction Ewing s sarcoma ES is a
2019-07-01
Introduction Ewing\'s sarcoma (ES) is a high-grade neoplasm representing the second most common primary bone malignancy in both children and adults. With a peak incidence at 15 years, this disease accounts for 2% of childhood cancers [1–3]. ES is defined as a bone tumor which may occur at any site
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LQTS is classified into subtypes
2019-07-01
LQTS is classified into subtypes LQT1 to LQT13 based on the site of genetic mutation. Each type possesses distinct clinical characteristics and a different prognosis. Treatment choice depends partly on individual phenotype and partly on genotype. Among Asian countries, several reports have been publ
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The congruence between BrS and ERS with
2019-07-01
The congruence between BrS and ERS with respect to clinical manifestations and response to therapy lends further support to the repolarization hypothesis. Using an experimental model of ERS, Koncz et al. [30]. recently provided evidence in support of the hypothesis that, similar to the mechanism ope
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Puromycin br Discussion Pericardial adhesions often develop
2019-07-01
Discussion Pericardial adhesions often develop after open Puromycin surgery, rendering a percutaneous subxiphoidal pericardial approach challenging [1–5]. Such adhesions are anticipated to be less dense in the inferior wall than in the anterior wall of the LV [1]. Therefore, there may be a chanc
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With the publication of this month s
2019-07-01
With the publication of this month\'s issue, we mark \'s first birthday. I hope you will allow me to effuse for a moment in the manner of a new parent discovering the fascination of her offspring\'s everyday achievements… Since its conception in March, 2013, the infant has maintained a healthy inta
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br Conflict of interest br
2019-06-29
Conflict of interest Introduction Cardiac resynchronization therapy (CRT) has become an important treatment for the management of Melanocyte stimulating hormone release inhibiting factor failure (HF) patients with left ventricular (LV) systolic dysfunction and a ventricular conduction delay [
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br Study limitations br Conflict of interest br Case report
2019-06-29
Study limitations Conflict of interest Case report Discussion DFT testing is usually recommended to ensure proper functioning of the ICD/CRT-D and verify that there is no acute lead dislodgement [1,2]. For patients with impaired cardiac function, VF induction and shock delivery can cause
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The patient started FOLFOX chemotherapy at another institute
2019-06-29
The patient started FOLFOX chemotherapy at another institute on September 14, 2015. However, he suddenly lost consciousness and his blood pressure plummeted; the electrocardiogram monitor showed ventricular tachycardia. After cardiopulmonary resuscitation, he regained spontaneous circulation and was
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br Introduction Once metastatic breast cancer cells
2019-06-29
Introduction Once metastatic breast cancer NVP 231 are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and degrade the bone
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p-gp inhibitors list br Contributors br Funding br
2019-06-29
Contributors Funding Conflict of interest Patient consent Ethics approval Acknowledgment Introduction Perforation of a cardiac chamber has been reported as a relatively rare complication of pacemaker implantation; in particular, attachment of the active-fixation atrial lead to t
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As with many global health estimates
2019-06-29
As with many global health estimates, data gaps contribute to substantial uncertainty intervals. To calculate their estimates Bourne and colleagues used data from 288 studies and more than 90 countries, but data gaps persist. For example, primary data were not available for approximately half the wo
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