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Many studies have also demonstrated that
2019-07-01
Many studies have also demonstrated that CK2 inhibition profoundly affects the PI3K/AKT pathway in different cancer models; promising results have been obtained in hematological malignancies (Buontempo et al., 2014, Borgo et al., 2013, Piazza et al., 2012, Cheong et al., 2010, Gowda et al., 2016), a
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Our results for imidacloprid were unexpected considering
2019-07-01
Our results for imidacloprid were unexpected: considering that imidacloprid (Im) is a neonicotinoid insecticide with a different mode of action (agonist of the nicotinic Ethacrynic acid - d5 receptor) than OPs, we expected Es-ChE and T-ChE activity to be largely insensitive to changes in Im concent
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Theoretically the expression profile of GluCl variants was
2019-07-01
Theoretically, the expression profile of GluCl variants was related to their physiological roles. It was reported that all the three variants (GluCl A, GluCl B, GluCl C) were highly expressed in head tissue of L. striatellus and M. domestica, and the expression level of GluCl A was significantly hig
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br Stephanie Topp points to the limitations of quality measu
2019-07-01
Stephanie Topp points to the limitations of quality measurement in Commission on High Quality Health Systems (HQSS Commission; May, 2017) that might not fit the real-world contexts of low-income and middle-income countries (LMICs). She also takes issue with a narrow set of generic indicators and t
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Induction of labor starting with
2019-07-01
Induction of labor starting with cervical ripening through the Foley catheter method has been a generally accepted technique and believed to be the safest method to manage pregnant women with an unfavorable TBCA of because it avoids exogenous uterine stimulants and relies on the local and endogenou
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regulator of g protein signaling In contrast median Cu level
2019-07-01
In contrast, median Cu level (0.73 mg/L) in our study was approximately 50% lower than that in maternal blood (1.47 mg/L). Our result is consistent with several previously published studies, which showed a 50–60% decrease in Cu level in the fetus. The observed decrease in fetal Cu, a major metallic
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Early repolarization is often also observed in
2019-07-01
Early repolarization is often also observed in Brugada syndrome patients [30–34]. In this study, 34% of Brugada syndrome patients exhibited early repolarization in inferolateral leads. Clinical characteristics, inducibility, and arrhythmic event rate were similar between patients with and without ea
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In the case reported by Goldstein
2019-07-01
In the case reported by Goldstein et al. [2], a Riata ST lead (St. Jude Medical, Sylmar, CA, USA) was used. The authors did not mention whether the lead was a dual-coil system or not. If the lead was a single-coil system, the possibility of an HV short circuit between the RV coil conductor and the d
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Brefeldin A The efficiency of additional strategies
2019-07-01
The efficiency of 2 additional strategies for eliminating the substrate for AF maintenance in addition to PVI has been described. Linear lesions are commonly made at the roof between the contralateral superior PVs (roof line), and at the isthmus between the mitral valve and the left inferior PV (mit
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Introduction Ewing s sarcoma ES is a
2019-07-01
Introduction Ewing\'s sarcoma (ES) is a high-grade neoplasm representing the second most common primary bone malignancy in both children and adults. With a peak incidence at 15 years, this disease accounts for 2% of childhood cancers [1–3]. ES is defined as a bone tumor which may occur at any site
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LQTS is classified into subtypes
2019-07-01
LQTS is classified into subtypes LQT1 to LQT13 based on the site of genetic mutation. Each type possesses distinct clinical characteristics and a different prognosis. Treatment choice depends partly on individual phenotype and partly on genotype. Among Asian countries, several reports have been publ
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The congruence between BrS and ERS with
2019-07-01
The congruence between BrS and ERS with respect to clinical manifestations and response to therapy lends further support to the repolarization hypothesis. Using an experimental model of ERS, Koncz et al. [30]. recently provided evidence in support of the hypothesis that, similar to the mechanism ope
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Puromycin br Discussion Pericardial adhesions often develop
2019-07-01
Discussion Pericardial adhesions often develop after open Puromycin surgery, rendering a percutaneous subxiphoidal pericardial approach challenging [1–5]. Such adhesions are anticipated to be less dense in the inferior wall than in the anterior wall of the LV [1]. Therefore, there may be a chanc
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With the publication of this month s
2019-07-01
With the publication of this month\'s issue, we mark \'s first birthday. I hope you will allow me to effuse for a moment in the manner of a new parent discovering the fascination of her offspring\'s everyday achievements… Since its conception in March, 2013, the infant has maintained a healthy inta
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br Conflict of interest br
2019-06-29
Conflict of interest Introduction Cardiac resynchronization therapy (CRT) has become an important treatment for the management of Melanocyte stimulating hormone release inhibiting factor failure (HF) patients with left ventricular (LV) systolic dysfunction and a ventricular conduction delay [
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